Epstein-Barr vaccine for ME/CFS?

We’ve been sort of chipping away at this [long COVID] by treating each symptom,” he says. “If it’s really true that at least 40% of people have significant recovery with a therapeutic vaccination, then, to date, this is the most effective intervention we have for long COVID.

Mysterious Ailment, Mysterious Relief: Vaccines Help Some COVID Long-Haulers, NPR

Quite a few who have Chronic Fatigue Syndrome (CFS) got it after an Epstein-Barr infection (mononucleosis), just like some got long-Covid following a Covid 19 infection.

Both are classic post-viral syndromes, so I wonder if an Epstein-Barr vaccine would help some of those CFS patients? Although most promising leads in medicine go nowhere, it would be worth testing.

Unfortunately, there is no approved vaccine for Epstein-Barr yet, but it may come. I assume it’s not a priority to develop this type of vaccine.

If this turns out to work for EB-related CFS, why would it? The trigger of CFS may be a low-grade chronic EB infection. So an EB vaccine may kick the immune system into better detecting and going after EB virus previously “invisible” to the immune system.

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